What kind of treatment did you have for your bone cancer?
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What is the treatment for bone cancer?
An operation to remove the cancer is the mainstay of treatment for bone cancers. Surgical techniques can remove most bone cancers without requiring amputation of the affected limb. Sometimes, muscles and other tissues that surround the cancer also have to be removed. Reconstructive surgery may be needed, in addition to cancer resection, to help maximize function of the limb.
Ewing sarcoma, osteosarcoma, and other bone cancers may require chemotherapy in addition to surgery.
Radiation therapy is the typical treatment for chondrosarcoma.
Ewing sarcomas that do not respond well to high-dose chemotherapy may require radiation therapy and even a stem-cell transplant. In this procedure, the patient's stem cells (blood cells that have the potential to develop into all the different kinds of blood cells) are harvested from the bloodstream. After high doses of chemotherapy medications to destroy the bone marrow, the harvested stem cells are next returned to the body, as with a blood transfusion. Over the next three to four weeks, the stem cells produce new blood cells from the bone marrow.
Targeted therapies are specially designed treatments that aim treatment specifically at the cancer cells. For example, denosumab (Xgeva) is a monoclonal antibody that acts to block the activity of specialized bone cells called osteoclasts. This medication has been used in the treatment of giant cell tumors of bone that have recurred after surgery or cannot be removed by surgery. Imatinib (Gleevec) is a targeted therapy drug that can block the signals from certain mutated genes that cause tumor cells to grow. Imatinib has been used to treat some chordomas that have spread or recurred after treatment.