Cyclospora Infection - Treatment

Please describe the treatment of your Cyclospora infection.

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What is the treatment of Cyclospora infections?

Cyclospora infection is self-limited, and mild or asymptomatic cases require no treatment. For those who require treatment, the best option is oral trimethoprim-sulfamethoxazole (TMP-SMX) (Bactrim, Septra) twice daily for seven days. For those who continue to have symptoms or have persistent oocysts on stool examination, another seven-day course is usually effective in clearing infection. For patients with a sulfa allergy, there are few good alternatives. There are reported cases where nitazoxanide (Alinia) twice daily was successful as an alternate therapy, although large-scale studies have not been done. One small study suggested that ciprofloxacin (Cipro, Cipro XR, Proquin XR) twice daily for seven days is an option in adults, but it has a higher failure rate compared to TMP-SMX and some have questioned its effectiveness. Because these medications are not approved for routine use during pregnancy, treatment of pregnant patients should be individualized and done in consultation with an obstetrician.

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