Rhabdomyolysis - Describe Your Experience

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What is rhabdomyolysis?

Rhabdomyolysis (RAB-DOE-MY-O-LIE-SIS) is the rapid destruction of skeletal muscle resulting in leakage into the urine of the muscle protein myoglobin.

There are three different types of muscle in the human body;

  1. smooth muscle,
  2. skeletal muscle, and
  3. heart muscle.

The skeletal muscle is the muscle of movement of the body (moving the skeleton at the joints). Skeletal muscle is affected by rhabdomyolysis.

Myoglobin is a protein component of the muscle cells that is released into the blood when the skeletal muscle is destroyed in rhabdomyolysis. Creatine kinase is an enzyme (a protein that facilitates chemical reactions in the body) also in the muscle cells. The level of each of these proteins can be measured in blood to monitor the degree of muscle injury from rhabdomyolysis. Myoglobin can also be measured in samples of urine.

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See what others are saying

Comment from: Sten cell1, 35-44 Male (Patient) Published: May 21

I had rhabdomyolysis in my right leg. I was unconscious for 19 hours, when I awoke on my right side on concrete floor I had purple dots on my leg. I tried to walk but my leg kept collapsing. After being admitted to hospital and diagnosed with rhabdomyolysis they flushed the muscle, out of my blood stream. Years later the nerve damage and muscle weakness remains. I am looking into stem cell trials with great interest.

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Comment from: cold war coastie, 75 or over Male (Patient) Published: May 23

I have enjoyed good health with mild hypertension managed by calcium channel blocker and diuretic, with regular blood pressure readings below 120/80. My cholesterol numbers are all outstanding. Following carotid scan which showed approximately 30% narrowing on both sides and was characterized as 'mild'. Primary care suggested 10 mg pravastatin to minimize future stroke risk. Forty-five days later I began to feel muscle pain in lower legs which increased in severity to a point it woke me for several days in succession. I returned to the doctor and CPK indicates mild rhabdomyolysis. I stopped statin and began rehydration/flush and will return for retest in a week or two. For me, statins are out and I suggest others be very careful when considering statin therapy.

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