If your relative is on a medication for Alzheimer's, what changes have you noticed?
Share your story with others:
MedicineNet appreciates your comment. Your comment may be displayed on the site and will always be published anonymously.
Partial glutamate antagonists
Glutamate is the major excitatory neurotransmitter in the brain. One theory
suggests that too much glutamate may be bad for the brain and cause
deterioration of nerve cells. Memantine (Namenda) works by partially decreasing
the effect of glutamate to activate nerve cells. It has not been proven that
memantine slows down the rate of progression of Alzheimer's disease. Studies have demonstrated
that some patients on memantine can care for themselves better than patients on
sugar pills (placebos). Memantine is approved for treatment of moderate and
severe dementia, and studies did not show it was helpful in mild dementia. It is
also possible to treat patients with both AchEs and memantine without loss of
effectiveness of either medication or an increase in side effects.