Naegleria fowleri - Causes

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If you, a friend, or relative had a Naegleria fowleri infection, what was the cause?

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What causes a Naegleria fowleri infection?

N. fowleri exposure occurs when people come into contact with warm freshwater through swimming, diving, water skiing, water toys, or other recreational activity. Public drinking water and well water also pose a risk. Although contact with infected water is common in the United States, symptomatic disease caused by N. fowleri is not often reported.

PAM occurs when N. fowleri is aspirated or forced high into the nasal cavity. The amoeba produces enzymes that digest mucus and protein, which it swallows up with its "feeding cups" or amoebastomes. N. fowleri is attracted to chemicals released by nerve cells. The olfactory nerves (nerves of smell) travel from the roof of the nasal cavity through perforations in the skull (cribriform plate) into the base of the brain. The amoeba consumes the nerve cells, migrating along these tracts until it reaches the brain. The brain is an especially rich food source, with high oxygen levels, glucose, and living cells. Damage to the brain is caused by severe inflammation, direct injury, and bleeding. Death is caused by the resulting severe brain swelling.

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Comment from: rkgold24k, 19-24 Male (Caregiver) Published: August 11

He was having CSF (cerebral spinal fluid) rhinorrhea and was using normal face wash daily. That might have caused his PAM (primary amebic meningoencephalitis) by Naegleria fowleri infection.

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