Urine Blockage in Newborns - Syndromes

Did your newborn have a particular syndrome that caused a urine blockage?

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Syndromes That May Affect the Urinary Tract

In addition to defects that occur in a single spot in the urinary tract, some babies are born with genetic conditions that affect several different systems in the body. A condition that includes multiple, seemingly unrelated problems, is called a syndrome.

  • Prune belly syndrome (PBS). Occurring only in boys, PBS causes a baby to have an enlarged abdomen because the normal abdominal wall muscles are missing or very weak. The entire urinary tract is enlarged, and both testicles remain inside the body instead of descending into the scrotum. The skin over the abdomen is wrinkled, giving the appearance of a prune. Most children with PBS have hydronephrosis and VUR.

  • Esophageal atresia (EA). EA is a birth defect in which the esophagus is incomplete. The esophagus is the tube that carries food from the mouth to the stomach. About 30 percent of babies born with EA will have problems in other body systems, such as the heart or urinary tract.

  • Congenital heart defects. Heart defects range from mild to life threatening. Children born with heart defects also have a higher rate of problems in the urinary tract than children in the general population, suggesting that some types of heart and urinary defects may have a common genetic cause.
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