Enterovirulent E. coli (EEC) - Treatment

What treatment methods did you receive for your enterovirulent E. coli infection?

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How are enterovirulent E. coli infections treated?

Initial treatment methods are similar for all of the EEC groups; hydration is the main treatment, both oral and IV (intervenous) hydration. However, additional treatment measures may be needed. If the patient is infected with EHEC, antibiotics are not used unless the patient is septic. Studies have shown that antibiotics in the EHEC group (especially with E. coli 0157:H7) induce bacteria that produce Shiga toxin to increase toxin release and make the disease and complications worse. In addition, investigators suggest that other toxin producing E. coli serovars in other groups (EPEC, ETEC and EIEC) may not be helped by antibiotics since on some rare occasions; they can develop complications similar to those of EHEC.

Although some cases of traveler's diarrhea have been treated with antibiotics (for example, sulfamethoxazole and trimethoprim [Septra]), in general, antibiotics may reduce symptoms by only about 24/48 hours. EAEC and EAggEC frequently are self-limiting and many of the serovars are resistant to one or more antibiotics. If the decision to use antibiotics in any EEC infection is made, investigators suggest the E. coli serovar causing the infection be tested to determine antibiotic susceptibilities.

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