Stiff-Person Syndrome - Treatment

Not ready to share? Read other Patient Comments

What was your treatment for Stiff-Person syndrome?

Share your story with others:

MedicineNet appreciates your comment. Your comment may be displayed on the site and will always be published anonymously.Patient Comments FAQs

Enter your Comment

Tell us a bit about your background to make your comments more useful to other MedicineNet users. (Optional)

Screen Name: *

Gender of Patient: Male Female

Age Range of Patient:

I am a: Patient Caregiver

* Screen Name will appear next to the published comment. Please do not include your full name or email address.

By submitting your comment, and other materials (collectively referred to as a "Submission") to MedicineNet, you grant MedicineNet permission to use, copy, transmit, publish, display, edit and modify your Submission in connection with its Web site. MedicineNet will not pay you for your Submission. You represent that you have all rights necessary for MedicineNet to use your Submission as set forth above.

Please keep these guidelines in mind when writing your comment:

  • Please make sure you address the question asked.
  • Due to the overwhelming number of comments received, not all comments will be published.
  • When selecting comments to publish, our staff will choose those that are educational and complement the topic. Please try to stay on topic.
  • Your comment may be edited. We would typically edit comments to make them clearer and more readable. We will remove personal information such as last names, email and web addresses, and other potentially harmful information.
  • We will not notify you if your comment has been published. We suggest that you check back on the topic article regularly.
  • We do not provide medical or healthcare advice, treatment, or diagnosis.

Thank you for participating!

I have read and agree to abide by the MedicineNet Terms and Conditions and the MedicineNet Privacy Policy (required).

To prevent our systems from spam, please complete the following prior to submitting your comment.

Please select the black square:

Is there any treatment for Stiff-Person syndrome?

People with Stiff-Person syndrome respond to high doses of diazepam and several anti-convulsants, gabapentin and tiagabine. A study funded by the NINDS demonstrated the effectiveness of intravenous immunoglobulin (IVIg) treatment in reducing stiffness and lowering sensitivity to noise, touch, and stress in people with Stiff-Person syndrome.

Return to Stiff-Person Syndrome

See what others are saying

Comment from: The Stiff Guy :P, 19-24 Male (Patient) Published: December 10

I have stiff-person syndrome. There are several treatments. Some of them only for pain in muscles. Some of them are for solving the reason of the syndrome. For the pain they can use baclofen, Lioresal 50 mg and Apranax Plus. I'm using the last two. I also tried the plasmapheresis two different times. First one was feeling so good for 4 months, after which the symptoms were start to back. First plasmapheresis included 5 doses with 5 units of albumin at every dose. The second plasmapheresis included 9 doses with real human plasma with 20 units of plasma at each dose. The second one didn't feel good for very long, only for 1 month. But some researching shows that IVIG can be good choice for treatment. Soon I will talk with my doctor.

Was this comment helpful?Yes
Comment from: Noemi, 55-64 Female (Patient) Published: December 16

If you are diagnosed with stiff-person syndrome (SPS) I suggest you see a neurologist as soon as possible and get immunoglobulin and Valium immediately. I was informed by one specialist that if you start the treatment you could go into remission, but I waited 1 year to start the treatment even though I think I had the disease for 3 years. But the doctors didn't know what I had, they thought I had back problems and depression. Since I am a registered nurse I was hesitant to start the immunoglobulin for the side effects as well as the Valium, silly me. Maybe I lost my chance to go into remission like one of the doctors told me, but now I am taking Valium, baclofen, gabapentin, immunoglobulin and some anxiety medicines like Prozac and Buspar. I am feeling better after 10 years, you should do some meditation and exercise too. Good luck.

Was this comment helpful?Yes


Get the latest health and medical information delivered direct to your inbox!

Health Solutions From Our Sponsors