Stiff-Person Syndrome - Symptoms

Not ready to share? Read other Patient Comments

What were your signs and symptoms associated with Stiff-Person syndrome?

Share your story with others:

MedicineNet appreciates your comment. Your comment may be displayed on the site and will always be published anonymously.Patient Comments FAQs

Enter your Comment

Tell us a bit about your background to make your comments more useful to other MedicineNet users. (Optional)

Screen Name: *

Gender of Patient: Male Female

Age Range of Patient:

I am a: Patient Caregiver

* Screen Name will appear next to the published comment. Please do not include your full name or email address.

By submitting your comment, and other materials (collectively referred to as a "Submission") to MedicineNet, you grant MedicineNet permission to use, copy, transmit, publish, display, edit and modify your Submission in connection with its Web site. MedicineNet will not pay you for your Submission. You represent that you have all rights necessary for MedicineNet to use your Submission as set forth above.

Please keep these guidelines in mind when writing your comment:

  • Please make sure you address the question asked.
  • Due to the overwhelming number of comments received, not all comments will be published.
  • When selecting comments to publish, our staff will choose those that are educational and complement the topic. Please try to stay on topic.
  • Your comment may be edited. We would typically edit comments to make them clearer and more readable. We will remove personal information such as last names, email and web addresses, and other potentially harmful information.
  • We will not notify you if your comment has been published. We suggest that you check back on the topic article regularly.
  • We do not provide medical or healthcare advice, treatment, or diagnosis.

Thank you for participating!

I have read and agree to abide by the MedicineNet Terms and Conditions and the MedicineNet Privacy Policy (required).

To prevent our systems from spam, please complete the following prior to submitting your comment.

Please select the white triangle:

What are the signs and symptoms of Stiff-Person syndrome?

Stiff-Person syndrome is characterized by fluctuating muscle rigidity in the trunk and limbs and a heightened sensitivity to stimuli such as noise, touch, and emotional distress, which can set off muscle spasms. Abnormal postures, often hunched over and stiffened, are characteristic of the disorder. People with Stiff-Person syndrome can be too disabled to walk or move, or they are afraid to leave the house because street noises, such as the sound of a horn, can trigger spasms and falls.

Return to Stiff-Person Syndrome

See what others are saying

Comment from: Glasgow, 35-44 Female (Patient) Published: August 28

I was being treated for panic attacks and anxiety for a period of 4 years. My groin and the bottom of my back would go into a spasm and my legs would be a dead weight. I had many falls and after one of them presented myself to ER where i was admitted for 2 weeks. For approx 4/5 days after this fall I could not walk with assistance. I have just recently being diagnosed with Stiff-Person syndrome and i am just waiting to start IVIG treatment which I hope will bring some normality back to my life.

Was this comment helpful?Yes
Comment from: Dwayne, 55-64 Female (Caregiver) Published: July 29

My wife was misdiagnosed with a dystonia for three years before the GAD test was performed last summer; the test indicated SPS. Since then, she has tried Valium, IVIG, plasma exchange, Rituxan, and baclofen infusion. An evaluation at the Mayo Clinic resulted in a prescribed dosage of Valium with a target of 150 mg per day, which she could not handle and has went through painful withdrawal after getting up to 100 mg. She walks with a cane, has developed an exaggerated lordotic curve in her back, has limited stamina, and has recently started having swelling and pain in her hands, feet, and ankles. She is also suffering with depression. The classic symptoms relating to loud noise, light, and emotional distress, all of which cause muscle spasms, have progressed with her disease. Our next option, apparently, is Cytoxan along with psychiatric intervention. She has had limited benefit from Valium and no positive effect from anything else.

Was this comment helpful?Yes


Get the latest health and medical information delivered direct to your inbox!