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What is the treatment for gynecomastia?
Gynecomastia, especially in pubertal males, often goes away on its own within
about six months, so observation is preferred over specific treatment in many
cases. Stopping any offending medications and treatment of underlying medical
conditions that cause gynecomastia are also mainstays of treatment.
Treatments are also available to specifically address the problem of
gynecomastia, but data on their effectiveness are limited, and no drugs have yet
been approved by the U.S. Food and Drug Administration (FDA) for treatment of
gynecomastia. Medications are more effective in reducing gynecomastia in the
early stages, since scarring often occurs after about 12 months. After the
tissue has become scarred, medications are not likely to be effective, and
surgical removal is the only possible treatment.
Medications that have been used to treat gynecomastia include:
Testosterone replacement has been effective in older men with low levels of
testosterone, but it is not effective for me who have normal levels of the male
Clomiphene, and anit-estrogen medication has been used to treat
gynecomastia. It can be taken for up to 6 months.
The selective estrogen receptor modulator (SERM)
has been shown to reduce breast volume in gynecomastia, it was not
able to entirely eliminate all the breast tissue. This type of therapy is most
often used for severe or painful gynecomastia.
Danazol is a synthetic derivative of testosterone that decreases estrogen synthesis by the testes. It works by inhibition of pituitary secretion of LH and follicle-stimulating hormone (FSH), substances that direct the sex organs to produce hormones. It is less commonly used to treat gynecomastia than other medications.