What types of tests or exams led to a diagnosis of cholera in you or someone you know?
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How do health-care professionals diagnose cholera?
Preliminary diagnosis is usually done by a caregiver who takes a history from the patient and observes the characteristic rice-water diarrhea, especially if a local outbreak of cholera has identified. The diarrhea fluid is often teeming with motile, comma-shaped bacteria (presumptively V. cholerae) that can be seen with a microscope. The definitive diagnosis is made by isolation of the bacteria from diarrhea fluid. All state health department laboratories in the U.S. are able to perform tests for
Vibrio cholerae. Readers may see terms like serotypes Inaba, Ogawa, and Hikojima to describe V. cholerae; they simply indicate which O antigens (O antigens designated A, B, or C) are found on these strains of V.
cholerae. PCR tests have also been developed to detect the genetic material of cholera, but currently they are not as widely used as the immunologic tests based on type-specific antiserum.
Definitive diagnosis helps to distinguish cholera from other diseases caused
by other bacterial, protozoal, or viral pathogens that cause dysentery
(gastrointestinal inflammation with diarrhea).