Liver Blood Tests - Diagnosis

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What blood tests are done to detect liver function?

The blood tests that truly reflect the liver function are the following:

  • Coagulation panel (prothrombin time or PT, and international normalized ratio or INR): These tests measure blood's ability for normal clotting and prevention of bleeding and bruising. This is the function of certain proteins called clotting factors that normally are produced in the liver.
  • Albumin level (hypoalbuminemia): Albumin is a very common protein found in the blood with a variety of functions. It also is produced only in the liver, and if its levels are lower than normal it can be suggestive of chronic liver disease or liver cirrhosis. Of note, Many conditions other than liver disease also may cause low albumin levels.
  • Bilirubin: This molecule is a byproduct of the routine destruction of red blood cells occurring in the liver. It is normally released as bile in the feces. Elevation of the bilirubin can suggest liver dysfunction. However, other conditions with increased destruction of red blood cells also can cause elevated bilirubin levels despite normal liver function.
  • Platelet count: Low platelet count (thrombocytopenia) has many causes, one of which can be advanced liver disease.
  • Glucose: Glucose level is maintained in the body by a variety of mechanisms. The liver can release glucose in the blood for nourishment of other cells in case of starvation with insufficient oral intake of glucose. This process, called gluconeogenesis, is another major function of the liver. In advanced liver disease, this function of the liver can be compromised leading to unusually low glucose levels in the absence of adequate oral intake. Liver function panel test generally encompasses AST, ALT numbers plus bilirubin, and albumin. In addition, coagulation panel and complete blood count (CBC) with platelet count are usually necessary for initial evaluation of liver problems.
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See what others are saying

Comment from: lowjoy, 55-64 Female (Patient) Published: December 16

My liver enzyme test results were, SGPT 2400 and the other was 2,323. Bilirubin is high and white blood count low. I am waiting for further tests. Levels were all fine 3 months back. I am diabetic but in good control by diet of carbs restriction to 20 or less a day.

Was this comment helpful?Yes
Comment from: Pratham, 45-54 Male (Caregiver) Published: November 11

My father's serum bilirubin, SGOT and SGPT values are 98, 191 and 329. He is suffering from hepatitis B. He is a diabetic patient.

Was this comment helpful?Yes


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