Connective Tissue Disease - Signs and Symptoms

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What were the signs or symptoms associated with a connective tissue disease in you or a relative?

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What are symptoms and signs of a connective tissue disease?

A common symptom of a connective tissue disease is nonspecific fatigue. Depending on which connective tissue disease is present, and how active it is, a wide variety of symptoms may occur. These include fevers, muscle and joint pain and stiffness, weakness, and many other symptoms. Please refer to our articles on each particular disease (see below) for more information about symptoms.

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See what others are saying

Comment from: Karen, 65-74 Female (Patient) Published: November 22

I have been having a problem with the tendons in my hands locking up during certain movements. My palms hurt and tonight for the first time, when the fingers locked, I was in pain and had a hard time unlocking the "lock up". Doctors don't seem to know what is wrong. I don't know where to go from here. Or even if this is a symptom of connective tissue disorder. Can't seem to find anything related to this problem.

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Comment from: cc, (Patient) Published: February 25

I will start by saying that I am/was a nurse until I fell too ill to work and exhibited many of the symptoms of connective tissue disease you all are discussing here. I began to realize that it was worse when eating specific foods/drinks so I took it upon myself to experiment with my intake and focused on the things I ate the most of. I have seen many doctors and like you all I had little to no relief. I also began developing a number of bone spurs throughout my body and read something about tea disease (also known as fluorosis). So realizing I drank at least a half-gallon of tea a day, I eliminated it from my diet and all my bone spurs resolved themselves with no surgery needed. I still have the joint pain, some days better than others now, but I also have difficulty with foods that are known to be high in sulfur. When I cut all this out I feel 75 percent better. I am not saying this is what you guys are suffering from but it is worth a try to eliminate the suffering. I miss my tea though. Best of luck.

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