Multiple Myeloma - Symptoms

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What were the symptoms of your multiple myeloma?

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What are multiple myeloma symptoms and signs?

Patients with myeloma may be found asymptomatic with an unexplained increase in protein in the blood. With more advanced disease, some myeloma patients may present with weakness due to anemia caused by inadequate production of red blood cells, with bone pain due to the aforementioned bone damage, and as the abnormal M protein can accumulate in and damage the kidneys thereby resulting in a patient being found to have otherwise unexplained kidney damage and decreased kidney function.

The following is a list symptoms and signs of multiple myeloma:

  • Anemia
  • Bleeding
  • Nerve damage
  • Skin lesions
  • Enlarged tongue (macroglossia)
  • Bone tenderness or pain
  • Weakness or tiredness
  • Infections
  • Pathologic bone fractures
  • Back pain
  • Spinal cord compression
  • Kidney failure and/or damage
  • Loss of appetite and weight loss
  • Constipation
  • Hypercalcemia
  • Leg swelling
Return to Multiple Myeloma

See what others are saying

Comment from: lisa s., 45-54 Female (Patient) Published: July 17

I am 48 years young, was an active person went to the gym 3 to 5 times a week. It started out I was tired all the time and sometimes weak, then a pain behind my left shoulder pain that went down my bicep. Then one day at work my back; I went to turn and my back cracked, not in a good way, and I lost my breath. To make a long story short a few days later I went to the hospital because by this time I could hardly walk. After 4 days of tests in the hospital I found out I had a fractured spine and also they found multiple myeloma. But if it wasn't for this one doctor I still probably wouldn't have known.

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Comment from: Susan, 45-54 Female (Patient) Published: March 08

I have had diabetes type II since I was 40, and every time there was a medical problem it was blamed on my diabetes. I worked in medical offices for many years. It started with having no energy. I would have to stop many times just to rest before clocking in. My heart had irregular heartbeats. I had neuropathy in my feet and hands. They said it is my diabetes. I had gynecologic cancer ten years earlier and had radiation and I thought I was home free. Then one day there was a lump on the middle of my forehead, it was the size of a small egg. I asked nurses, doctors, and nurse practitioners. I kept getting infections. 'It's the diabetes,' or 'did you bump your head?' That's what they kept asking. I kept telling them no. I knew something was wrong. It was a first year resident that did the right tests, and listened to my symptoms instead of saying it is diabetes. I have stage III multiple myeloma and I am thankful this doctor came my way. The other doctors gave him a hard time, but he didn't give up.

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