What kinds of treatment, including medication, did you receive for C. difficile colitis?
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How is C. difficile colitis treated?
Treatment of C. difficile colitis includes:
correction of dehydration and
electrolyte (mineral) deficiencies,
discontinuing the antibiotic that caused the
using antibiotics to eradicate the C. difficile bacterium.
patients with mild colitis, stopping the antibiotic that caused the infection
may be enough to cause the colitis and diarrhea to subside. In most cases,
however, antibiotics are needed to eradicate the C. difficile bacteria.
Antibiotics that are effective against C. difficile include
(Flagyl), and vancomycin (Vancocin). These two antibiotics usually are taken
orally for 10 days. Both antibiotics are equally effective. With either
antibiotic, fever usually will resolve in one or two days, and diarrhea in three
or four days.
The choice of which antibiotic to use depends on the individual patient's
situation and the preferences of the treating doctor. Some doctors will
prescribe metronidazole first because it is much cheaper than vancomycin.
Vancomycin is reserved for patients who do not respond to metronidazole, are
allergic to metronidazole, or develop side effects from metronidazole. Other
doctors will prescribe vancomycin first for severe colitis because vancomycin
can achieve much higher antibiotic levels in the colon than metronidazole (and
higher antibiotic levels theoretically would be more effective in killing