Crohn's Disease - Medications

Not ready to share? Read other Patient Comments

What medications have you taken for Crohn's disease? Have any of them helped with symptoms?

Share your story with others:

MedicineNet appreciates your comment. Your comment may be displayed on the site and will always be published anonymously.Patient Comments FAQs

Enter your Comment

Tell us a bit about your background to make your comments more useful to other MedicineNet users. (Optional)

Screen Name: *

Gender of Patient: Male Female

Age Range of Patient:

I am a: Patient Caregiver


* Screen Name will appear next to the published comment. Please do not include your full name or email address.

By submitting your comment, and other materials (collectively referred to as a "Submission") to MedicineNet, you grant MedicineNet permission to use, copy, transmit, publish, display, edit and modify your Submission in connection with its Web site. MedicineNet will not pay you for your Submission. You represent that you have all rights necessary for MedicineNet to use your Submission as set forth above.

Please keep these guidelines in mind when writing your comment:

  • Please make sure you address the question asked.
  • Due to the overwhelming number of comments received, not all comments will be published.
  • When selecting comments to publish, our staff will choose those that are educational and complement the topic. Please try to stay on topic.
  • Your comment may be edited. We would typically edit comments to make them clearer and more readable. We will remove personal information such as last names, email and web addresses, and other potentially harmful information.
  • We will not notify you if your comment has been published. We suggest that you check back on the topic article regularly.
  • We do not provide medical or healthcare advice, treatment, or diagnosis.

Thank you for participating!


I have read and agree to abide by the MedicineNet Terms and Conditions and the MedicineNet Privacy Policy (required).

To prevent our systems from spam, please complete the following prior to submitting your comment.

Please select the white circle:

Crohn's Disease Medications

There is no medication that can cure Crohn's disease. Patients with Crohn's disease typically will experience periods of relapse (worsening of inflammation) followed by periods of remission (lessening of inflammation) lasting months to years. During relapses, symptoms of abdominal pain, diarrhea, and rectal bleeding worsen. During remissions, these symptoms improve. Remissions usually occur because of treatment with medications or surgery, but occasionally they occur spontaneously without any treatment.

Since there is no cure for Crohn's disease, the goals of treatment are to 1) induce remissions, 2) maintain remissions, 3) minimize side effects of treatment, and 4) improve the quality of life. Treatment of Crohn's disease and ulcerative colitis with medications is similar though not always identical.

Medications for treating Crohn's disease include

  1. anti-inflammatory agents such as 5-ASA compounds and corticosteroids,
  2. topical antibiotics, and
  3. immuno-modulators.

Selection of treatment regimens depends on disease severity, disease location, and disease-associated complications. Various guidelines recommend that approaches be sequential - initially to induce clinical remission, and then to maintain remissions. Initial evidence of improvement should be seen within 2 to 4 weeks and maximal improvement should be seen in 12 to 16 weeks3. The classic approach to therapy in Crohn's disease has been a "step-up" approach starting with the least toxic agents for mild disease, and increasingly more aggressive treatment for more severe disease, or patients who have not responded to less toxic agents. More recently the field has been moving toward a "top-down" approach (early aggressive management) which might decrease exposure to anti-inflammatory agents and increase exposure to agents that enhance mucosal healing that might prevent future complications4.

Return to Crohn's Disease

See what others are saying

Comment from: Molly, 35-44 Female (Patient) Published: January 17

I have been on so many medications for Crohn's disease but Cimzia has made a huge difference for me! I was very scared about a biologic drug but it has made it possible to have a life outside my bathroom. I can spend time with my children and go do things. Eat something other than liquid or soft blah foods. I love Cimzia.

Was this comment helpful?Yes
Comment from: Robert, 65-74 Male (Patient) Published: October 31

I suffered for about 2 1/2 years before finding a treatment to relieve my symptoms. It began suddenly, just prior to an overseas trip which had to be cancelled. I began to see fresh blood in my stool and by the next day I probably had a high fever (because I had hallucinations during the night but no thermometer) and felt very weak and nauseous. I saw my primary doctor and he arranged a colonoscopy, scheduled in six weeks. Two years, two colonoscopies, one camera swallow, countless blood tests and four gastroenterologists later I started budesonide and began getting relief from the continuous bloody diarrhea. In the interim, I had tried Asacol, Pentasa, Lialda, balsalazide, mesalamine, enemas and prednisone. I seem to be in remission now on 3mg of budesonide daily.

Was this comment helpful?Yes

STAY INFORMED

Get the latest health and medical information delivered direct to your inbox!