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Blood Clots - Causes

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What was the cause of your blood clot?

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What causes blood clots?

Blood clots form when there is damage to the lining of a blood vessel, either an artery or a vein. The damage may be obvious, such as a laceration, or may occur on the microscopic level. As well, blood will begin to clot if it stops moving and becomes stagnant.

Venous thrombosis or blood clots in a vein occur when a person becomes immobilized and muscles are not contracting to push blood back to the heart. This stagnant blood begins to form small clots along the walls of the vein. This initial clot can gradually grow to partially or completely occlude or block the vein and prevent blood from returning to the heart. An analogy to this process is a slow moving river. Over time, weeds and algae start to accumulate along the banks of the river where the water flows more slowly. Gradually, as the weeds start to grow, they begin to invade the center of the river because they can withstand the pressure of the oncoming water flow.

Arterial thrombi (blood clots in an artery) occur by a different mechanism. For those with atherosclerotic disease, plaque deposits form along the lining of the artery and grow to cause narrowing of the vessel. This is the disease process that may cause heart attack, stroke, or peripheral artery disease. If a plaque ruptures, a blood clot can form at the site of that rupture and can completely or partially occlude the blood flow at that point.

Blood clots in the heart. In atrial fibrillation, the atrium or upper chamber of the heart does not beat in an organized manner. Instead, it jiggles, and blood tends to become stagnant along the walls of the atrium. Over time, this may cause small blood clots to form. Clots can also form in the ventricle after a heart attack when part of the heart muscle is injured and unable to contract normally. Since the damaged area doesn't contract with the rest of the heart, blood can start to pool or stagnate, leading to clot formation.

Blood leaking out of a blood vessel.  Blood clots can form when blood leaks out of a blood vessel. This is very beneficial when a person gets a cut or scrape wound, because the clot helps stop further bleeding at the wound site. The clotting mechanism works well following trauma as well. Broken bones, sprains and strains, and nosebleeds all result in bleeding that is controlled by the body's clotting mechanism.

Blood clots causing other medical problems. Sometimes, normal blood clotting can cause medical problems because of its location. For example, if bleeding occurs in the urine from any of a variety of reasons (such as infection, trauma, or tumor) clots may form and prevent the bladder from emptying, causing urinary retention. Clot formation in the uterus may cause pain when the clots are passed through the cervix and can lead to vaginal bleeding, either as part of menstruation or as abnormal vaginal bleeding (menorrhagia, dysmenorrhea).

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See what others are saying

Comment from: Martell34, 45-54 Male (Patient) Published: November 23

I walked into the emergency room after my left calf became swollen and hot to the touch. I ended up having DVT behind my left knee from mid-thigh to the top of my calf. I also had blood clots in both my lungs. I had been having problems for about 3 weeks prior with my calf feeling like it needed to be stretched out and felt like it was cramping. Thought it was just overworked from exercise, maybe strained and it would go away. About a week before I went in, I noticed being short of breath walking up a flight of stairs. Being physically fit, I started to wonder about a blood clot. If you suffer these symptoms, don't wait and get it checked out! What I thought was a strained calf muscle almost killed me!

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Comment from: 55-64 Female Published: August 29

I had a hysterectomy and 3 weeks later, after a 5 hour car ride (no break), I could not get a deep breath and was coughing. I generally didn't feel well, and had a weakness in my arms and legs. I was in the hospital six days with a pulmonary embolism in both lungs. I had a heparin IV and was eventually put on Coumadin. I go weekly for blood tests and haven't gotten blood regulated yet, it's been a week and a half since I'm out of the hospital. I was told I will be on Coumadin for about 6 to 9 months and then will need further testing to see if I am now prone to clotting and therefore may have to take it the rest of my life.

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