Ca 125 - Results

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How is CA 125 measured?

CA 125 is usually measured from a venous blood sample. It can also be measured in fluid from the chest or abdominal cavity. The tests currently in use are all based upon the use of an antibody that is directed against the CA 125 protein (monoclonal antibody technique).

In 1991, an improved version of the test was introduced and is sometimes denoted as CA 125 - II. The numerical figure of the second generation test results may be higher or lower than a first generation test. The first generation test is no longer used. When comparing multiple CA 125 test results over time, it can be important to know which method was used.

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See what others are saying

Comment from: A2nA2, 45-54 Female (Patient) Published: August 21

CA 125 before surgery was 32. Mass was intact with no cancer on the outside. Level was 65 after surgery with surgical spill. Dropped to 25 after first chemotherapy and 10 after second chemotherapy.

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Comment from: Gabby, 45-54 Female (Patient) Published: May 31

My doctor did and ultrasound because of bad cramping. The first year they said I had fibroids. I went back the next year and they did another ultrasound. They said I didn't have fibroids, but I had a cyst on my right ovary. They did a CA 125 test and it was 44. So they sent me to a gynecologist. Before I went to the gynecologist they did another CA 125 test. At the gynecologist's, they did an ultrasound. They said I did have fibroids and that they cyst on my right ovary was smaller, but that I had a cyst on my left ovary also. They did a CA 125. It came back as 33. They next day I got a call from my regular doctor about the second CA 125 they did. It came back as 61. So I am very confused. First, 44 then 61 then 33. First fibroids, then no fibroids. First cyst on right ovary, then cyst on left ovary.

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