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Pancreatic Cancer
(Cancer of the Pancreas)

Pancreatic Cancer Symptoms and Signs

What are the symptoms and signs of pancreatic cancer?

Pancreatic cancer has been called a "silent" disease because early pancreatic cancer usually does not cause symptoms. If the tumor blocks the common bile duct and bile cannot pass into the digestive system, the skin and whites of the eyes may become yellow, and the urine may become darker. This condition is called jaundice. As the cancer grows and spreads, pain often develops in the upper abdomen and sometimes spreads to the back. The pain may become worse after the person eats or lies down. Cancer of the pancreas can also cause nausea, loss of appetite, weight loss, and weakness. A rare type of pancreatic cancer, called islet cell cancer, begins in the cells of the pancreas that produce insulin and other hormones. Islet cells are also called the islets of Langerhans. Islet cell cancer can cause the pancreas to produce too much insulin or hormones. When this happens, the patient may feel weak or dizzy and may have chills, muscle spasms, or diarrhea. These symptoms may be caused by cancer or by other, less serious problems. If an individual is experiencing symptoms, a doctor should be consulted.

What are symptoms and signs of cancer of the pancreas? Learn about pancreatic cancer symptoms »


What is the pancreas?

The pancreas is a spongy, tube-shaped organ about 6 inches long. It is located in the back of the abdomen, behind the stomach. The head of the pancreas is on the right side of the abdomen. It is connected to the duodenum, the upper end of the small intestine. The narrow end of the pancreas, called the tail, extends to the left side of the body.

The pancreas makes pancreatic juices and hormones, including insulin. Pancreatic juices, also called enzymes, help digest food in the small intestine. Insulin controls the amount of sugar in the blood. Both enzymes and hormones are needed to keep the body working right.

As pancreatic juices are made, they flow into the main pancreatic duct. This duct joins the common bile duct, which connects the pancreas to the liver and the gallbladder. The common bile duct, which carries bile (a fluid that helps digest fat), connects to the small intestine near the stomach.

What is cancer?

Cancer is a group of diseases. More than 100 different types of cancer are known, and several types of cancer can develop in the pancreas. They all have one thing in common: abnormal cells grow and destroy body tissue.

Healthy cells that make up the body's tissues grow, divide, and replace themselves in an orderly way. This process keeps the body in good repair. Sometimes, however, some cells lose the ability to control their growth. They grow too rapidly and without any order. Too much tissue is made, and tumors are formed. Tumors can be benign or malignant.

Benign tumors are not cancer. They do not spread to other parts of the body and are seldom a threat to life. Often, benign tumors can be removed by surgery, and they are not likely to return.

Malignant tumors are cancer. They can invade and destroy nearby healthy tissues and organs. Cancer cells also can break away from the tumor and spread to other parts of the body. The spread of cancer is called metastasis.

Cancer that starts in the pancreas is called pancreatic cancer. When pancreatic cancer spreads, it usually travels through the lymphatic system. The lymphatic system includes a network of thin tubes that branch, like blood vessels, into tissues all over the body. Cancer cells are carried through these vessels by lymph, a colorless, watery fluid that carries cells that fight infection. Along the network of lymphatic vessels are groups of small, bean-shaped organs called lymph nodes. Surgeons often remove lymph nodes near the pancreas to learn whether they contain cancer cells.

Cancer cells can also be carried through the bloodstream to the liver, lungs, bone, or other organs. Pancreatic cancer that spreads to other organs is called metastatic pancreatic cancer.

Pancreas (Pancreatic Cancer)
Picture of pancreas in an article on pancreatic cancer
Cancer that starts in the pancreas is called pancreatic cancer. This picture of the pancreas shows its location in the back of the abdomen, behind the stomach.


Next: What causes cancer of the pancreas? »

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Pancreatic Cancer

What is the pancreas?

The pancreas is an organ approximately six inches long that is located in the abdomen behind the stomach. The pancreas is divided into three regions; the head, the body, and the tail. The head of the pancreas is located in the right abdomen adjacent to the duodenum, the tail is in the left abdomen, and the body lies between the head and the tail.

The pancreas makes several hormones that are released into the blood--including insulin to regulate blood glucose levels (see the Diabetes Mellitus article)-as well as digestive enzymes that aid in the digestion of food, for example, amylase. The digestive enzymes produced by the pancreas are combined in a bicarbonate-rich fluid also produced by the pancreas. The pancreatic duct within the pancreas collects the bicarbonate-rich fluid and digestive enzymes and drains them into the duodenum, the first part of the small intestine just beyond the stomach.

The co...

Read the Pancreatic Cysts article »











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