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GENERIC NAME: CHLORAMPHENICOL/FIBRINOLYSIN/DNASE - TOPICAL OINTMENT (klor-am-FEN-eh-coal/fye-brin-oh-LIE-sin/DEE-naze)

BRAND NAME(S): Elase-Chloromycetin

Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

WARNING: Very rarely, serious, even fatal, blood disorders (e.g., bone marrow hypoplasia, aplastic anemia) have occurred while using this medication. Do not use chloramphenicol if safer, effective medications can be used. Immediately notify your doctor if you have easy bruising or bleeding, persistent sore throat, fever, or unusual fatigue.

USES: This medication breaks up and helps remove dead skin and tissue to encourage healing of wounds. It is used to promote healing of wounds and treat minor infections associated with burns, ulcers, surgical wounds, circumcision or episiotomy.

HOW TO USE: This medication is for topical or vaginal use only. To apply to the skin, first clean the wound as directed and gently dry the area. Apply a thin layer of ointment and cover the area with gauze or a bandage as recommended. Change the bandage 1 to 3 times a day as directed. For maximal effects, the wound must be cleaned before applying new ointment. For vaginal use, insert the prescribed amount of ointment deep into the vagina once a night as directed. Do not apply this in large amounts or use this more often than directed. Wash hands well after applying the ointment.

SIDE EFFECTS: This medication may temporarily cause redness, irritation, itching or swelling of the area. If these symptoms continue or become bothersome, inform your doctor. Notify your doctor if you experience a skin rash, breathing trouble, unusual bruising or bleeding, weakness. If you notice other effects not listed above, contact your doctor or pharmacist.




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  • Episiotomy - Learn about episiotomy procedure where an incision is made between the vagina and anus to assist in vaginal birth. Complications, risks, and frequency of episiotomy are discussed in the information.
  • Peptic Ulcer - Learn about peptic ulcers, a hole in the gut lining of the stomach, duodenum, or esophagus.
  • Burns (First Aid) - Burns are categorized by severity as first, second, or third degree. First degree burns are similar to a painful sunburn. The damage is more severe with second degree burns, leading to blistering and more intense pain. The skin turns white and loses sensation with third degree burns. Burn treatment depends upon the location, total burn area, and intensity of the burn.

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chloramphenicol-fibrinolysin-dnase-topical ointment, Elase-Chloromycetin

Introduction to burns

The skin has an important role to play in the fluid and temperature regulation of the body. If enough skin area is injured, the ability to maintain that control can be lost. The skin also acts as a protective barrier against the bacteria and viruses that inhabit the world outside the body.

The anatomy of the skin is complex, and there are many structures within the layers of the skin. There are three layers:

  1. Epidermis, the outer layer of the skin
  2. Dermis, made up of collagen and elastic fibers and where nerves, blood vessels, sweat glands, and hair follicles reside.
  3. Hypodermis or subcutaneous tissue, where larger blood vessels and nerves are located. This is the layer of tissue that is most important in temperature regulation.

The amount of damage that a burn can cause depends upon its location, its depth, and how much body surface area that it involves.

...

Read the Burns (First Aid) article »




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