Medical Definition of PustulosisPustulosis: A highly inflammatory skin condition that results in large, fluid-filled, blister-like areas (pustules). Pustulosis typically occurs on the palms of the hands and/or the soles of the feet. The skin of these areas peels and flakes (exfoliates). Last Editorial Review: 5/13/2016 Back to MedTerms online medical dictionary A-Z List Need help identifying pills and medications? |


