A Novel Medication to Help Quit Smoking

Medical Author: Melissa Conrad Stoppler, MD
Medical Editor: Jay W. Marks, MD

In May 2006, the U.S. Food and Drug Administration (FDA) approved the medication Chantix (varenicline tartrate) to help cigarette smokers stop smoking . Chantix received a priority FDA review because of its potential, important benefit to public health.

Varenicline tartrate is unique in that it mimics the actions of nicotine on the brain and can help both in easing nicotine withdrawal symptoms and blocking the reinforcing effects of nicotine if smoking is resumed. Two reports in the August 14/28, 2006 issue of the Archives of Internal Medicine have demonstrated the effectiveness of varenicline in both short- and long-term smokers who wish to quit smoking. The researchers report that treatment with varenicline tartrate led to response rates three times higher than placebo in smokers aged 18 to 65 who were attempting to quit smoking.