Premature Ejaculation: Breaking the Silence (cont.)
There have been other surveys and studies where the figure has been lower -- somewhere between 10% and 20%. I think that somewhere around the 27% to 34%, somewhere in that range, is probably the most accurate number. It is a very common problem.
However, when we do studies on this, it's important to have some objective - "something you can hang your hat on" kind of data. So, we time ejaculation in those studies. We did what was called an observational study and when we looked at people in society, surveyed them and found a group of people without premature ejaculation and a group of people with premature ejaculation. We found that people with premature ejaculation did have significantly shorter times to ejaculate than the men without PE. In other words, they ejaculated much quicker than people that claimed they did not have premature ejaculation.
In doing these studies we have defined premature ejaculation in saying that, for these particular studies looking at dapoxetine, you had to have ejaculated less than two minutes in 75% of intercourse attempts.
The two-minute cut-off tends to be a good one, but I have to say that it's not a definition. In other words, somebody can come in to my office and say they ejaculate at one and a half minutes, and not have premature ejaculation -- it may be just when they want, when their partner wants and it may not cause any distress so that person does not have PE. On the other hand, you may have somebody who comes in and ejaculates four minutes after penetration and it may be causing a tremendous amount of distress for both the patient and the partner. So, there's no rigid time cut-off in real life. We use the two minutes, although somewhat artificial, because we needed to have some definition for the study so that the FDA could look at the results with some sort of objectivity.
In addition, in the observational study that we did, people who tended to ejaculate sooner claim that they didn't have control and people who did not the have PE claimed that they feel like they did have control.
There's also some data that we have to suggest that if you ejaculate and it's over a minute, that you're going to be much more satisfied with your sexual experience than if it's less than a minute. There's numerous data out there to suggest, in general, that if ejaculation is in less than two minutes, people are not happy with that.
I think that they should also go to a knowledgeable physician in this area. This tends to be urologist, though not all of them will know about PE, but many of them do.
My suggestion is -- don't suffer, try to get some treatment. Today, in May of 2005, there's no therapy specific for premature ejaculation. They are going to have to try things like numbing medications or other medications that may have some side effects. Hopefully in the near future there will be something that's indicated specifically for premature ejaculation.
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