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RU-486

RU-486: Coming Soon to a Provider Near You

By Tula Karras
WebMD Feature

May 5, 2000 -- Women will soon have another choice when it comes to unwanted pregnancies. The forthcoming drug, Mifeprex (mifepristone, formerly known in Europe as RU-486), offers women a medical abortion without the need for surgery. The Food and Drug Administration (FDA) is expected to approve the drug in the next few months.

Advocates of Mifeprex and other medical abortion drugs are hopeful that this new option will continue to fuel the trend of women making choices early on. "Any type of abortion that is performed in the first seven weeks of a pregnancy is extremely safe, but with medical abortions there's no anesthesia necessary and no surgery," says Richard Hausknecht, MD, a professor at Mount Sinai School of Medicine.

Hausknecht has been performing abortions in the United States since 1970, when they were first legalized. "The earlier the abortion is performed, the better," he says. "Medical abortions can be performed as soon as a woman knows she's pregnant, whereas most abortion clinics have women wait until they are at least seven weeks pregnant before performing a surgical abortion -- though a well-trained doctor can perform one at five weeks."

For years Hausknecht has been using methotrexate (which terminates the pregnancy) and misoprostol (which causes the uterus to contract), drugs that are not approved by the FDA for medical abortion, but are used off-label for that very purpose.