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Is Your Medication Working Overtime?

Many medications on the market today are prescribed for one condition but have been found to help others as well. Is your drug doing double duty?

By Carol Sorgen
WebMD Feature

Reviewed By Michael Smith

Many medications on the market today are prescribed for one condition but have been found to help others as well. Is your drug doing double duty?

"Many drugs do have added benefits," says Marc Siegel, MD, clinical associate professor at New York University School of Medicine. Aspirin, for example, can not only treat headaches, but it also reduces the risk of heart attack and has been shown to possibly lower the risk of breast and colon cancer, to name just a few of its benefits.

Sometimes a drug is studied for one purpose and is then found to have another effect. Siegel says researchers investigating Viagra as a heart medication, for example, found that it caused erections; as a result, it became a best-selling treatment for erectile dysfunction. It has also been found to be an effective therapy for altitude sickness and can reverse the libido-lowering effect of antidepressants in women, Siegel says.

Beta-blockers are another multipurpose class of drugs, Siegel says. They not only lower blood pressure, but they can also be used to treat the pain of angina, slow heart rate and prevent disturbances in heart rhythm, prevent migraines, and stave off panic attacks and stage fright by preventing a surge in adrenaline.

Antianxiety medications such as Valium and Xanax can also be used as muscle relaxants, Siegel says.

Prescribing a medication for a condition other than that for which the drug has received FDA approval is a common occurrence, says Siegel, and is called prescribing "off label." "FDA guidelines are helpful, but they're not an all-or-nothing ruling. As long as the drug is on the market, it's OK for the doctor to use his judgment when prescribing it."

What is not OK, he says, is for patients to start medicating themselves. Just because you've read, for example, that antidepressants can ease hot flashes does not mean that it's all right to borrow a handful of someone else's pills.

"Never take anyone else's medicine," Siegel cautions. "These are prescription drugs and they're by prescription for a reason. Always call your doctor and ask for his or her recommendation for your individual condition."

Statins Do Double Duty

With that warning given, Siegel goes on to say that there are a number of other medications on the market that also show more than one benefit.

As mentioned above, the latest generation of antidepressants, such as Prozac and Effexor, can reduce hot flashes by as much as 50%, making them a possible alternative for women who can't or don't want to take hormone replacement therapy.

The drugs known as statins, which are used primarily to lower cholesterol, are showing much promise when it comes to fighting a number of other conditions. Recent studies have shown that statins may lessen the risk of bone fractures in older women, although the results are not conclusive yet and researchers are calling for further investigation.

Statins are also being recommended for nearly all patients with type 2 diabetes. In guidelines released by the American College of Physicians in the April 20, 2004, issue of the Annals of Internal Medicine, lead researcher Vincenza Snow, MD, recommended that anyone with type 2 diabetes and at least one heart disease risk factor should be taking one of the statins. The risk factors are:

  • 55 or older
  • High blood pressure
  • High LDL "bad" cholesterol (LDL over 100)
  • Smoking
  • Physical inactivity
  • Obesity
  • Existing heart disease

Diuretics, which are used to treat high blood pressure by reducing fluid levels in the body, are believed to reduce the risk of Alzheimer's disease by as much as 75%, according to research reported at the 9th International Conference on Alzheimer's Disease and Related Disorders. Once Alzheimer's disease has developed, the oral diabetes medicine Avandia may improve memory and thinking ability in people with a mild form of the disease.

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