Hypothyroidism Symptoms
Medical Author: Melissa Stoppler, M.D.
Medical Editor:
William C. Shiel, Jr, MD, FACP, FACR
The thyroid gland is a
butterfly-shaped organ situated on the front of the neck that secretes two hormones, thyroxine (also known as T4) and
triiodothyronine
(called T3), that are important in the control of metabolism.
Hypothyroidism is a condition in which the thyroid gland does not produce
adequate levels of these critical hormones.
Hypothyroidism is very common and is estimated to affect
3-5% of the adult population. It is more common in women
than in men, and the risk of developing hypothyroidism increases with advancing
age.
Hypothyroidism is most commonly a result of an
autoimmune condition known as Hashimoto's thyroiditis, in
which the body's own immune cells attack and
destroy the thyroid gland. Since the activity of the thyroid gland is controlled
by other hormones from the pituitary gland and the
hypothalamus of the brain,
defects in these areas can also cause underactivity of the thyroid gland.
Previous surgeries on the thyroid or a history of irradiation to the neck are
other causes of hypothyroidism.
Symptoms of hypothyroidism can be mild or
severe, but are often very subtle. People with a mild form of the condition may
not have any symptoms at all. The most serious form of hypothyroidism is called
myxedema, which can lead to coma and even death. An underactive thyroid gland
affects all organs and functions within the body, leading to both physical and
emotional symptoms. Some of the most common symptoms of hypothyroidism in adults
are:
- Tiredness and
weakness; feeling "run down"
- Weight gain or difficulty losing weight
- Constipation
- Depression
- Thinning or brittleness of the hair or nails
- Cold intolerance
- Sleepiness
- Memory loss
- Decreased libido
- Muscle aches and pains
Those affected by more advanced cases of hypothyroidism
may notice dryness or thickening of the skin; slow speech; abnormal menstrual
cycles; puffiness of the face, hands, or feet; and decreased capacity for taste
and smell.
If you are experiencing symptoms of hypothyroidism, your
doctor can order simple blood tests to diagnose the condition. An underactive thyroid gland
is in most cases easily and completely treated by daily administration of
thyroid hormones in tablet form.
Last Editorial Review: 9/28/2006