Medical Definition of Leiomyosarcoma

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Leiomyosarcoma: A malignant tumor that originates in smooth muscle, the major structural component of most hollow internal organs and the walls of blood vessels. Leiomyosarcoma can occur almost anywhere in the body but is most frequently found in the uterus and gastrointestinal tract. Complete surgical excision, if possible, is the treatment of choice.

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