Definition of Juvenile polyposis syndrome

Juvenile polyposis syndrome: An autosomal dominant disorder in which polyps develop throughout the gastrointestinal tract in the first decade or two of life. People with the disease are at increased risk for developing gastrointestinal cancers. Abbreviated JPS. There can also be diarrhea, GI bleeding, and protein-losing from the intestinal wall. JPS is clearly heterogeneous (more than one entity) as regards causation. Some cases of JPS appear sporadic with no family history of juvenile polyposis, while other cases are due to mutations in the MADH4 gene on chromosome 18 or the BMPR1A gene on chromosome 10. Also known as juvenile intestinal polyposis (JIP), juvenile polyposis coli (JPC).

Last Editorial Review: 3/19/2012

Children's Health Pictures Slideshow: Top 10 Brain Foods for Children

Search MedTerms:

Back to MedTerms online medical dictionary A-Z List
Pill Identifier Tool

Need help identifying pills and medications?
Use the pill finder tool on RxList.

Health Solutions From Our Sponsors