Medical Definition of Systemic mastocytosis
Systemic mastocytosis: A form of mastocytosis characterized by infiltrates of mast cells in the skin, lymph nodes, liver, spleen, gastrointestinal tract, bones, and joints with a predisposition to peptic ulcer due to excess stomach acid (caused by the release of histamine from the mast cells).
Last Editorial Review: 6/9/2016
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