Definition of Base excision repair
Base excision repair: A process of DNA repair in which an altered base is excised (removed) by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is then filled in by the sequential action of DNA polymerase and DNA ligase. Abbreviated BER.
Last Editorial Review: 6/14/2012
Back to MedTerms online medical dictionary A-Z List
Need help identifying pills and medications?