Medical Definition of ParicalcitolParicalcitol: A man-made form of vitamin D. Brand name: Zemplar. In 1998 paricalcitol was approved by the FDA for the treatment of secondary hyperparathyroidism due to chronic renal failure. It causes less elevation of calcium than calcitriol, another vitamin D analogue and is associated with a lower mortality rate than calcitriol in patients on long-term dialysis. Last Editorial Review: 6/9/2016
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