Doctor's Responses Archive

Viewer Question:

I have been diagnosed with A.S. - but was wondering if the medication provided-being Celebrex-or the condition itself - may effect my moods! I have had a series of small bouts of depression (lasting up to a week) recommendations to alleviate the problem.
Signed, CM

Doctor's Response:

Depression has been reported in 0.1 - 1.9% of patients taking Celebrex.

Depression is more common in patients with Ankylosing Spondylitis, especially when it is actively causing pain and stiffness from chronic inflammation. Depression in this setting is best managed with a two-pronged approach: (a) addressing the underlying inflammation with rest, anti-inflammation medications, and possibly 'second-line' medicines (such as Azulfidine or methotrexate and (b) managing depression by stress-reduction techniques, relaxation methods, exercises, and possibly medications.

Thank you for your question.

Last Editorial Review: 2/1/2005

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