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Viewer Question My husband is on 300 mg a day of zyloprim for the
treatment of gout, even though to his knowledge he has never had an actual gout
attack. The only way he found out was when he had a blood test done for what
turned out to be a problem with his knee, that was fixed through arthroscopic
surgery. He has been on zyloprim for about 5 years. Is this
normal? When he asks his doctor, he tells him it is to prevent any
possible kidney damage. Doctor's Answer Significantly abnormally elevated uric acid blood levels can lead to damage to the tissues of the kidney (called urata nephropathy) and kidney stones. Allopurinol (zyloprim) is used to return the uric acid blood level to normal and avoid the risk of kidney damage, whether or not a patient has ever had gouty arthritis. Thank you for your question. Last Editorial Review: 12/30/2004
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