Arthritis Q&A by Dr. Shiel

Answer:

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The major reason that prednisone is tapered, rather than simply discontinued, is that prednisone when taken for an extended period of time, can suppress the ability of the adrenal glands to produce natural cortisone. This is because the adrenal glands can shrink (atrophy) when chronically exposed to prednisone. When our bodies can't make natural cortisone, it can lead to low blood pressure, nausea, vomiting, dizziness, and abdominal pain. This is called adrenal insufficiency.

Slow tapering of prednisone minimizes the risk of adrenal insufficiency.

Some people also develop muscle and/or joint aching (called steroid withdrawal symptoms) when prednisone is tapered too rapidly or discontinued.

Thank you for your question.