Viewer Question:I was recently diagnosed with Rheumatoid Arthritis (1 month ago). I have been to a Rheumatologist already and many tests have been taken. My Rheumatoid factor was 301 and x-ray results reflected deterioration in 2 joints of the left foot. After careful consideration, I have decided to enter the Remicade research study program which lasts 1 year. I just had all the initial testing last week for this study and will start the infusions. I have been reading about this study and I saw something about side affects by the placebo group and side affects from the people who actually received the drug. I have a few questions that hopefully you can answer for me:
Doctor's Response:Side effects are reported in placebo treated patients in all studies. They occur because when any large group of people is observed over time, they will note various symptoms. When a study is done, symptoms must be reported - whether or not they are suspected of being related to a medication. Many persons that are taking placebo in a study could also be taking other medicines or develop illnesses that could cause reportable symptoms.
If the study is double blinded, you will not be informed whether you are receiving the drug or placebo. "Double-blinded" means that neither the study patient nor the doctor know which is given.
Side effects can occur at any time with either. Your doctor will give the best opinion as to cause
Thank you for your question.
Last Editorial Review: 1/20/2003