Definition of Genoplasty
Genoplasty: A technology that uses the repair mechanisms normally present in cells to repair gene defects.
In genoplasty, a short oligonucleotide fragment is introduced into the cell to simulate a normal DNA sequence and this deceives the cell into repairing itself. The sequence of the gene itself is thus changed permanently.
Genoplasty is different from gene therapy in which a normal gene is inserted into the cell.
Last Editorial Review: 7/1/2016
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