From Our 2012 Archives

Mediterranean Diet May Protect Brain

Mediterranean Diet May Reduce Small Blood Vessel Damage in the Brain

By Jennifer Warner
WebMD Health News

Reviewed by Louise Chang, MD

Feb 13, 2012 -- Chalk up another possible benefit to following a Mediterranean diet.

A new study suggests that people who follow a Mediterranean-style diet have less small blood vessel damage in the brain.

The Mediterranean diet is based on the diets of the populations bordering the Mediterranean Sea, such as Italy and Greece.

The diet emphasizes fresh fruits and vegetables, fish, whole grains, legumes, monounsaturated fats like olive oil, and moderate amounts of alcohol. It has a low amount of red meat, saturated fats like butter, and refined grains.

Mediterranean Diet May Protect Blood Vessels

Eating a Mediterranean diet has already been linked to a lower risk of what's called the metabolic syndrome, heart disease, stroke, and dementia.

But researchers say no study has looked at the diet's possible link to white matter hyperintensity volume (WMHV) in the brain, which might help explain some of these beneficial effects.

WMHV is an indicator of small blood vessel damage in the brain and is detected by magnetic resonance screening (MRI). WMHV can be found in the average person as he or she ages. Previous studies have shown that high amounts of WMHV in the brain can predict a higher risk of stroke and dementia.

In the study, researchers compared the brain scans and diets of 966 adults with an average age of 72. The participants' reported diets were rated according to how closely they followed a Mediterranean diet.

The results showed that those who most closely followed a Mediterranean diet had a lower measure of WMHV than those who did not. Each increase in the Mediterranean diet score was associated with a corresponding decrease in white matter hyperintensity volume score.

This benefit remained consistent even after adjusting for other risk factors for small blood vessel damage in the brain, like smoking, diabetes, high blood pressure, and abnormal cholesterol levels.

Diet as a Whole Important

Researchers say the aspect of the Mediterranean diet that seemed to matter most was the ratio of monounsaturated fat to saturated fat.

Monounsaturated fats are found in many vegetable oils, avocados, and nuts. Saturated fats are mainly found in meat and dairy products, as well as in some processed foods.

But researcher Hannah Gardener, ScD, of the University of Miami Miller School of Medicine, and colleagues say their results suggest that "overall dietary pattern, rather than any of the individual components," may be more relevant in explaining the healthy benefits of the Mediterranean diet.

The results appear in the Archives of Neurology.

SOURCES: Gardener, H. Archives of Neurology, February 2012.News release, American Medical Association.Medscape News Today: "The Clinical Importance of White Matter Hyperintensities on Brain Magnetic Resonance Imaging: Systematic Review and Meta-Analysis."

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