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For example, many people are intolerant of lactose, the sugar in milk. In some individuals, even small amounts of milk can cause symptoms that mimic irritable bowel syndrome. Therefore, testing for lactose intolerance or a trial of strict elimination of lactose from the diet may be necessary in patients in whom a diagnosis of irritable bowel syndrome is being considered.
Individuals also may be intolerant of sucrose and may develop symptoms (diarrhea and cramps) that can mimic irritable bowel syndrome when they drink beverages like sodas that are sweetened with corn syrup which is high in sucrose.
Sorbitol is another example of a sweetener used in reduced calorie foods, for example, sugar-free chewing gum. It also is used in prepared foods and for diabetics. Intolerance to sorbitol may cause irritable bowel-like symptoms as well.
This illustrates the difficulty in firmly making a diagnosis of irritable bowel syndrome; you really have to sort out all of these different entities. (Remember, the diagnosis of IBS requires the exclusion of other diseases that can produce similar symptoms.)
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