Progressive multifocal leukoencephalopathy

Medical Definition of Progressive multifocal leukoencephalopathy

Progressive multifocal leukoencephalopathy: A rapidly progressive, often fatal viral infection of the brain. Commonly abbreviated as PML.

PML is believed to be due to the Jacob-Creutzfeldt (JC) papovavirus. The virus infects oligodendrocytes (support cells in the brain).

The signs and symptoms of PML include headaches, memory loss, changes in mental status, speech and vision difficulties, loss of strength, limb weakness, seizures, partial paralysis and loss of coordination. The disease leads to coma and then to death.


Quick Guide8 First Aid Kit Essentials for Scrapes, Cuts, Bug Bites, and More in Pictures

8 First Aid Kit Essentials for Scrapes, Cuts, Bug Bites, and More in Pictures

Subscribe to MedicineNet's General Health Newsletter

By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time.

Reviewed on 5/13/2016

Health Solutions From Our Sponsors