scopolamine, Transderm-Scop (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
STORAGE: Transderm Scop should be stored at room temperature 15-30 C (59-86 F).
PRESCRIBED FOR: Transderm Scop is used for the prevention of nausea and vomiting after surgery or resulting from motion sickness.
DOSING: To prevent nausea after surgery 1 patch is applied behind the ear (both ears for caesarian section) 1 hour before surgery and left in place for 24 hours.
The recommended adult dose for preventing motion sickness is one disc every three days. The disc is applied to the hairless area behind the ear at least 4 hours before the effects are desired. If therapy is needed for more than three days, the first disc is discarded, and a second disc is applied behind the opposite ear. To prevent contact with eyes and visual disturbances, the hands should be washed with soap and water after handling the patch.
DRUG INTERACTIONS: Alcohol, tranquilizers, sedatives, and other drugs that cause drowsiness may worsen the drowsiness caused by scopolamine. Scopolamine slows passage of materials including drugs through the stomach and intestines. This may reduce the absorption of some drugs. Drugs that have anticholinergic effects increase the anticholinergic side effects of scopolamine. Examples of such drugs include belladonna alkaloids, antihistamines (including meclizine [Antivert, Bonine, Meni-D, Antrizine]), tricyclic antidepressants, and muscle relaxants.
PREGNANCY: Use in pregnant women has not been adequately evaluated.
NURSING MOTHERS: Scopolamine is excreted in breast milk.
SIDE EFFECTS: The most common side effects are drowsiness, dry mouth, blurred vision, and dilation of the pupils. Scopolamine may worsen narrow angle glaucoma, cause difficulty urinating and lead to dry, itchy eyes. Some patients may experience disorientation and confusion. If used more than 3 days some patients may experience withdrawal symptoms such as nausea, vomiting, headache, and dizziness. Some patches may cause burns of the skin if worn during an MRI (magnetic resonance imaging) scan. Patients should tell their health care professional that they are using a medication patch prior to receiving an MRI scan, and the patch should be removed.
Reference: FDA Prescribing Information
Last Editorial Review: 3/21/2012
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