The following are health and medical definitions of terms that appear in the Schizophrenia article.
Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer).
Acute: Of abrupt onset, in reference to a disease. Acute often also connotes an illness that is of short duration, rapidly progressive, and in need of urgent care. See the entire definition of Acute
Antidepressant: Anything, and especially a drug, used to prevent or treat depression. See the entire definition of Antidepressant
Antidepressants: Anything, and especially a drug, used to prevent or treat depression. See the entire definition of Antidepressants
Antipsychotic: A medication (or another measure) that is believed to be effective in the treatment of psychosis. For example, aripiprazole (Abilify) is an antipsychotic medication used to treat schizophrenia.
Anxiety: A feeling of apprehension and fear characterized by physical symptoms such as palpitations, sweating, and feelings of stress. Anxiety disorders are serious medical illnesses that affect approximately 19 million American adults. These disorders fill people's lives with overwhelming anxiety and fear. Unlike the relatively mild, brief anxiety caused by a stressful event such as a business presentation or a first date, anxiety disorders are chronic, relentless, and can grow progressively worse if not treated. See the entire definition of Anxiety
Anxiety disorder: A chronic condition characterized by an excessive and persistent sense of apprehension with physical symptoms such as sweating, palpitations, and feelings of stress. Anxiety disorders have biological and environmental causes. See the entire definition of Anxiety disorder
Autism: A spectrum of neuropsychiatric disorders characterized by deficits in social interaction and communication, and unusual and repetitive behavior. Some, but not all, people with autism are non-verbal. See the entire definition of Autism
Bipolar disorder: A mood disorder sometimes called manic-depressive illness or manic-depression that characteristically involves cycles of depression and elation or mania. Sometimes the mood switches from high to low and back again are dramatic and rapid, but more often they are gradual and slow, and intervals of normal mood may occur between the high (manic) and low (depressive) phases of the condition. The symptoms of both the depressive and manic cycles may be severe and often lead to impaired functioning. See the entire definition of Bipolar disorder
Borderline personality disorder: A serious mental illness characterized by pervasive instability in moods, interpersonal relationships, self-image, and behavior. This instability often disrupts family and work life, long-term planning, and the individual's sense of self-identity. See the entire definition of Borderline personality disorder
Breastfeeding: Feeding a child human breast milk. According to the American Academy of Pediatrics, human breast milk is preferred for all infants. This includes even premature and sick babies, with rare exceptions. It is the food least likely to cause allergic reactions; it is inexpensive; it is readily available at any hour of the day or night; babies accept the taste readily; and the antibodies in breast milk can help a baby resist infections. See the entire definition of Breastfeeding
Catatonic:1. Characterized by marked motor abnormalities including immobility (catalepsy or stupor), excessive motor activity (purposeless agitation), extreme negativism, mutism, posturing or stereotyped movements, echolalia, and/or echopraxia. 2. A person with catatonia or catatonic schizophrenia.
Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time. See the entire definition of Chronic
Cognitive: Pertaining to cognition, the process of knowing and, more precisely, the process of being aware, knowing, thinking, learning and judging. The study of cognition touches on the fields of psychology, linguistics, computer science, neuroscience, mathematics, ethology and philosophy. See the entire definition of Cognitive
Cymbalta: Brand name for duloxetine hydrochloride, a drug approved by the FDA to treat major depresssion in adults and to manage the pain associated with diabetic peripheral neuropathy, nerve damage in diabetes. The drug acts as a serotonin and norepinephrine reuptake inhibitor, increasing the levels of serotonin and norepinephrine, two neurotransmitters, or chemical messengers, believed to be important in regulating a person's emotions as well as reducing the sensitivity to pain.
Depression: An illness that involves the body, mood, and thoughts, that affects the way a person eats and sleeps, the way one feels about oneself, and the way one thinks about things. A depressive disorder is not the same as a passing blue mood. It is not a sign of personal weakness or a condition that can be wished away. People with a depressive disease cannot merely "pull themselves together" and get better. Without treatment, symptoms can last for weeks, months, or years. Appropriate treatment, however, can help most people with depression. See the entire definition of Depression
Diagnosis:1 The nature of a disease; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies. 3 The identification of any problem. The diagnosis was a plugged IV. See the entire definition of Diagnosis
Dizziness: Painless head discomfort with many possible causes including disturbances of vision, the brain, balance (vestibular) system of the inner ear, and gastrointestinal system. Dizziness is a medically indistinct term which laypersons use to describe a variety of conditions ranging from lightheadedness, unsteadiness to vertigo. See the entire definition of Dizziness
Dopamine: An important neurotransmitter (messenger) in the brain. See the entire definition of Dopamine
Dyskinesia: Difficulty or distortion in performing voluntary movements, as in tic, chorea, spasm, or myoclonus. The term dyskinesia may be used in relation to Parkinson's disease and other extrapyramidal disorders. Dyskinesia can occur as a side effect of certain medications such as L-dopa and the antipsychotics. See the entire definition of Dyskinesia
Electroconvulsive therapy: A procedure in which an electric current is passed through the brain to produce controlled convulsions (seizures) to treat patients with depression, particularly for those who cannot take or are not responding to antidepressants, have severe depression, or are at high risk for suicide. Electroconvulsive therapy (ECT) is believed to act by a massive neurochemical release in the brain due to the controlled seizure. The most common side effect is short-term memory loss, which usually resolves quickly. ECT typically relieves depression within 1 to 2 weeks after beginning treatments.
Epilepsy (seizure disorder): When nerve cells in the brain fire electrical impulses at a rate of up to four times higher than normal, this causes a sort of electrical storm in the brain, known as a seizure. A pattern of repeated seizures is referred to as epilepsy. Known causes include head injuries, brain tumors, lead poisoning, maldevelopment of the brain, genetic and infectious illnesses. But in fully half of cases, no cause can be found. Medication controls seizures for the majority of patients.
Fetus: The unborn offspring from the end of the 8th week after conception (when the major structures have formed) until birth. Up until the eighth week, the developing offspring is called an embryo.
Genes: The basic biological units of heredity. Segments of deoxyribonucleic acid (DNA) needed to contribute to a function. See the entire definition of Genes
Genetic: Having to do with genes and genetic information.
Hormone: A chemical substance produced in the body that controls and regulates the activity of certain cells or organs. See the entire definition of Hormone
Intervention: The act of intervening, interfering or interceding with the intent of modifying the outcome. In medicine, an intervention is usually undertaken to help treat or cure a condition. For example, early intervention may help children with autism to speak. "Acupuncture as a therapeutic intervention is widely practiced in the United States," according to the National Institutes of Health. From the Latin intervenire, to come between.
Lipid: Another word for "fat." (Please see the various meanings of Fat.) A lipid is more formally defined as a substance such as a fat, oil or wax that dissolves in alcohol but not in water. Lipids contain carbon, hydrogen and oxygen but have far less oxygen proportionally than carbohydrates. See the entire definition of Lipid
Lithium: Lithium carbonate (brand names: Eskalith; Lithobid), a drug used as a mood stabilizer for the treatment of manic/depressive (bipolar) disorder. It prevents or diminishes the intensity of episodes of mania in bipolar patients. Typical symptoms of mania include pressure of speech, motor hyperactivity, reduced need for sleep, flight of ideas, grandiosity, elation, poor judgment, aggressiveness and possibly hostility. See the entire definition of Lithium
Manic: Refers to a mood disorder in which a person seems "high", euphoric, expansive, sometimes agitated, hyperexcitable, with flights of ideas and speech.
Marijuana: A very common street and recreational drug that comes from the marijuana plant. See the entire definition of Marijuana
Memory:1. The ability to recover information about past events or knowledge. 2. The process of recovering information about past events or knowledge. 3. Cognitive reconstruction. The brain engages in a remarkable reshuffling process in an attempt to extract what is general and what is particular about each passing moment. See the entire definition of Memory
Multiple personality disorder: A neurosis in which the personality becomes dissociated into two or more distinct parts each of which becomes dominant and controls behavior from time to time to the exclusion of the other parts.
Muscle: Muscle is the tissue of the body which primarily functions as a source of power. There are three types of muscle in the body. Muscle which is responsible for moving extremities and external areas of the body is called "skeletal muscle." Heart muscle is called "cardiac muscle." Muscle that is in the walls of arteries and bowel is called "smooth muscle."
NIH: The National Institutes of Health. The NIH is an important U.S. health agency. It is devoted to medical research. Administratively under the Department of Health and Human Services (HHS), the NIH consists of 20-some separate Institutes and Centers. NIH's program activities are represented by these Institutes and Centers. See the entire definition of NIH
Nurse: 1) A person trained, licensed, or skilled in nursing. 2) To feed an infant at the breast.
Onset: In medicine, the first appearance of the signs or symptoms of an illness as, for example, the onset of rheumatoid arthritis. There is always an onset to a disease but never to the return to good health. The default setting is good health. See the entire definition of Onset
Personality disorder: A disorder characterized by the chronic use of mechanisms of coping in an inappropriate, stereotyped, and maladaptive manner. Personality disorders are enduring and persistent styles of behavior and thought, not atypical episodes. The personality disorders encompass a group of behavioral disorders that are different and distinct from the psychotic and neurotic disorders. The official psychiatric manual, the DSM-IV (Diagnostic and Statistical Manual of the American Psychiatric Association, Fourth Edition), defines a personality disorder as an enduring pattern of inner experience and behavior that differs markedly from the expectations of the individual's culture, is pervasive and inflexible, has an onset in adolescence or early adulthood, is stable over time, and leads to distress or impairment. Personality disorders are a long-standing and maladaptive pattern of perceiving and responding to other people and to stressful circumstances. See the entire definition of Personality disorder
Pregnancy: The state of carrying a developing embryo or fetus within the female body. This condition can be indicated by positive results on an over-the-counter urine test, and confirmed through a blood test, ultrasound, detection of fetal heartbeat, or an X-ray. Pregnancy lasts for about nine months, measured from the date of the woman's last menstrual period (LMP). It is conventionally divided into three trimesters, each roughly three months long. See the entire definition of Pregnancy
Pregnant: The state of carrying a developing fetus within the body. See the entire definition of Pregnant
Prognosis:1. The expected course of a disease. 2. The patient's chance of recovery. The prognosis predicts the outcome of a disease and therefore the future for the patient. His prognosis is grim, for example, while hers is good. See the entire definition of Prognosis
Prolactin: A hormone secreted by the pituitary gland. Prolactin stimulates lactation (milk production). It also has many other functions, including essential roles in the maintenance of the immune system. See the entire definition of Prolactin
Psychiatric: Pertaining to or within the purview of psychiatry, the medical specialty concerned with the prevention, diagnosis, and treatment of mental illness. See the entire definition of Psychiatric
Psychiatrist: A physician (an M.D.) who specializes in the prevention, diagnosis, and treatment of mental illness. Psychiatrists must receive additional training and serve a supervised residency in their specialty. They may also have additional training in a psychiatric specialty, such as child psychiatry or neuropsychiatry. They can prescribe medication, which psychologists cannot do. See the entire definition of Psychiatrist
Psychosis: In the general sense, a mental illness that markedly interferes with a person's capacity to meet life's everyday demands. In a specific sense, it refers to a thought disorder in which reality testing is grossly impaired. See the entire definition of Psychosis
Rehabilitation: The process of restoration of skills by a person who has had an illness or injury so as to regain maximum self-sufficiency and function in a normal or as near normal manner as possible. For example, rehabilitation after a stroke may help the patient walk again and speak clearly again. See the entire definition of Rehabilitation
Relapse: The return of signs and symptoms of a disease after a patient has enjoyed a remission. For example, after treatment a patient with cancer of the colon went into remission with no sign or symptom of the tumor, remained in remission for 4 years, but then suffered a relapse and had to be treated once again for colon cancer. See the entire definition of Relapse
Residual: Something left behind. With residual disease, the disease has not been eradicated.
Resistance: Opposition to something, or the ability to withstand it. For example, some forms of staphylococcus are resistant to treatment with antibiotics.
Schizoaffective disorder: A mood disorder that is coupled with some symptoms resembling those of schizophrenia, particularly loss of personality (flat affect) and/or social withdrawal.
Schizophrenia: One of several brain diseases whose symptoms that may include loss of personality (flat affect), agitation, catatonia, confusion, psychosis, unusual behavior, and withdrawal. The illness usually begins in early adulthood. See the entire definition of Schizophrenia
Schizotypal personality disorder: A type of personality characterized by unusual patterns of speech and behavior and by social withdrawal. See the entire definition of Schizotypal personality disorder
Sensitivity:1. In psychology, the quality of being sensitive. As, for example, sensitivity training, training in small groups to develop a sensitive awareness and understanding of oneself and of ones relationships with others. 2. In disease epidemiology, the ability of a system to detect epidemics and other changes in disease occurrence. 3. In screening for a disease, the proportion of persons with the disease who are correctly identified by a screening test. 4. In the definition of a disease, the proportion of persons with the disease who are correctly identified by defined criteria.
Serotonin: A hormone, also called 5-hydroxytryptamine, in the pineal gland, blood platelets, the digestive tract, and the brain. Serotonin acts both as a chemical messenger that transmits nerve signals between nerve cells and that causes blood vessels to narrow. See the entire definition of Serotonin
Split personality: Multiple personality disorder, a neurosis in which the personality becomes dissociated into two or more distinct parts each of which becomes dominant and controls behavior from time to time to the exclusion of the other parts.
SSRI: Abbreviation for selective serotonin reuptake inhibitors, commonly prescribed drugs for treating depression. SSRIs affect the chemicals that nerves in the brain use to send messages to one another. These chemical messengers, called neurotransmitters, are released by one nerve and taken up by other nerves. Neurotransmitters that are not taken up by other nerves are taken up by the same nerves that released them. This process is termed "reuptake." SSRIs work by inhibiting the reuptake of serotonin, an action which allows more serotonin to be available to be taken up by other nerves. See the entire definition of SSRI
Substance:1. Material with particular features, as a pressor substance. 2. The material that makes up an organ or structure. Also known in medicine as the substantia. 3. A psychoactive drug as, for example, in substance abuse.
Substance abuse: The excessive use of a substance, especially alcohol or a drug. (There is no universally accepted definition of substance abuse.) See the entire definition of Substance abuse
Symptom: Any subjective evidence of disease. Anxiety, lower back pain, and fatigue are all symptoms. They are sensations only the patient can perceive. In contrast, a sign is objective evidence of disease. A bloody nose is a sign. It is evident to the patient, doctor, nurse and other observers.
Tardive dyskinesia: A neurological syndrome characterized by repetitive, involuntary, purposeless movements caused by the long-term use of certain drugs called neuroleptics used for psychiatric, gastrointestinal and neurological disorders such as Parkinson's disease. Features may include grimacing, tongue protrusion, lip smacking, puckering and pursing, and rapid eye blinking. Rapid movements of the arms, legs, and trunk may also occur. Impaired movements of the fingers may appear as though the patient is playing an invisible guitar or piano. The incidence of the syndrome rises with the dose and duration of drug treatment. The treatment of tardive dyskinesis is usually to stop or minimize the use of the offending drug. However, for some patients with a severe underlying condition this may not be a feasible option. Replacing the offending drug with substitute drugs may help. Other drugs such as benzodiazepines, adrenergic antagonists, and dopamine agonists may also be beneficial. In an individual case, the symptoms of tardive dyskinesia may remain long after discontinuation of the offending drug or the symptoms may improve or disappear with time.
Viable: Capable of life. For example, a viable premature baby is one who is able to survive outside the womb.
Weight loss: Weight loss is a decrease in body weight resulting from either voluntary (diet, exercise) or involuntary (illness) circumstances. Most instances of weight loss arise due to the loss of body fat, but in cases of extreme or severe weight loss, protein and other substances in the body can also be depleted. Examples of involuntary weight loss include the weight loss associated with cancer, malabsorption (such as from chronic diarrheal illnesses ), and chronic inflammation (such as with rheumatoid arthritis).
Depression is an illness that involves the body, mood, and thoughts and affects the way a person eats and sleeps, the way one feels about oneself, and the way one thinks about things. The principal types of depression are major depression, dysthymia, and bipolar disease (also called manic-depressive disease).
Alcoholism is a disease that includes alcohol craving and continued drinking despite repeated alcohol-related problems, such as losing a job or getting into trouble with the law.
Suicide is the process of intentionally ending one's own life. Approximately 1 million people worldwide commit suicide each year, and 10 million to 20 million attempt suicide annually.
Bipolar disorder (or manic depression) is a mental illness characterized by depression, mania, and severe mood swings. Treatment may incorporate mood stabilizer medications, antidepressants, and psychotherapy.
Dissociative identity disorder (formerly known as multiple personality disorder or split personality disorder) is a mental illness in which a person has at least two distinct personalities. Symptoms and signs include lapses in memory, feeling unreal, blackouts in time, hearing voices in their head that are not their own, not recognizing themselves in the mirror, and finding items in one's possession but not recalling how they were acquired. Treatment usually involves psychotherapy, medications, and sometimes hypnosis.
Drug addiction is a chronic disease that causes drug-seeking behavior and drug use despite negative consequences to the user and those around him. Though the initial decision to use drugs is voluntary, changes in the brain caused by repeated drug abuse can affect a person's self-control and ability to make the right decisions and increase the urge to take drugs. Drug abuse and addiction are preventable.
Antisocial personality disorder (ASPD) has many symptoms, signs, and causes. Therapy is one treatment option for antisocial personality disorder. It is closely related to other personality disorders (PD), such as borderline personality disorder and narcissistic personality disorder.
Psychotic disorders are a group of serious illnesses that affect the mind. Different types of psychotic disorders include schizophrenia, schizoaffective disorder, schizophreniform disorder, brief psychotic disorder, shared psychotic disorder, delusional disorder, substance-induced psychotic disorder, paraphrenia, and psychotic disorders due to medical conditions.
Schizoaffective disorder is a mental illness that features schizophrenia and a mood disorder, either major depression or bipolar disorder. Symptoms include agitation, suicidal thoughts, little need for sleep, delusions, hallucinations, and poor motivation. Treatment may involve psychotherapy, medication, skills training, or hospitalization.
Mental illness is any disease or condition affecting the brain that influence the way a person thinks, feels, behaves, and/or relates to others. Mental illness is caused by heredity, biology, psychological trauma and environmental stressors.
Compulsive gambling is a disorder that affects millions in the U.S. Symptoms and signs include a preoccupation with gambling, lying to family or loved ones to hide gambling, committing crimes to finance gambling, and risking importance relationships and employment due to gambling. Treatment may incorporate participation in Gamblers' Anonymous, psychotherapy, and medications like carbamazepine, topiramate, lithium, naltrexone, antidepressants, clomipramine, and fluvoxamine.
About 5 million children and adolescents in the U.S. suffer from a serious mental illness such as eating disorders, anxiety disorders, disruptive behavior disorders, pervasive development disorders, elimination disorders, learning disorders, schizophrenia, tic disorders, and mood disorders. Symptoms of mental illness include frequent outbursts of anger, hyperactivity, fear of gaining weight, excessive worrying, frequent temper tantrums, and hearing voices that aren't there. Treatment may involve medication, psychotherapy, and creative therapies.
Brief psychotic disorder is a short-term mental illness that features psychotic symptoms. There are three forms of brief psychotic disorder. The first occurs shortly after a major stress, the second has no apparent trauma that triggers the illness, and the third is associated with postpartum onset. Symptoms include hallucinations, delusions, unusual behavior, disorientation, changes in eating and sleeping, and speech that doesn't make sense. Treatment typically involves medication and psychotherapy.
Factitious disorders are conditions in which people pretend to have physical or mental illnesses when they aren't sick. These people may lie about or fake symptoms to obtain the sympathy and attention given to people who are genuinely ill. Symptoms of factitious disorders include dramatic, inconsistent medical history, the presence of many surgical scars, and a history of seeking treatment at many different hospitals.
During the ECT procedure, an electric current is passed through the brain to
produce controlled convulsions (seizures).
Why is electroconvulsive therapy performed?
ECT is useful for certain patients with significant depression,
particularly for those who cannot take or are not responding to antidepressants,
have severe depression, or are at a high risk for suicide. ECT often is
effective in cases where antidepressant medications do not provide sufficient
relief of symptoms.
How does electroconvulsive therapy work?
This procedure probably works by a
massive neurochemical release in the brain due to the controlled seizure. Highly
effective, ECT relieves depression within 1 to 2 weeks after beginning
treatments. After ECT, some patients will continue to have maintenance ECT,
while others will return to antidepressant medications.
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