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Sedative medications (CNS depressants)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.
Sassafras might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking sassafras along with sedative medications might cause too much sleepiness.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.