sargramostim, Leukine (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

DOSING: Sargramostim is administered intravenously or subcutaneously (under the skin). Sargramostim vials should not be shaken since the drug may be damaged, and bubbles may form that can prevent some of the drug from being drawn up into the syringe at the time of injection. Doses and duration of treatment vary depending on which condition it is used for. 250 mcg/m2/day given by intravenous injection is a typical adult dose for most uses.

DRUG INTERACTIONS: No clinical studies have been done to determine if sargramostim interacts with other drugs.

PREGNANCY: There are no studies of the use of sargramostim in pregnant women.

NURSING MOTHERS: There are no studies to determine if sargramostim is excreted into breast milk.

SIDE EFFECTS: The most common side effects while taking sargramostim are stomach pain, mild to moderate fever, weakness, chills, headache, nausea, vomiting, diarrhea, rash, muscle and bone pain. Shortness of breath, weight loss, leg and arm swelling, and injection site reactions also occur. Sargramostim may cause serious allergic reactions and abnormal heart beats.

Reference: FDA Prescribing Information

Last Editorial Review: 3/20/2013

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