- What is sargramostim, and how does it work (mechanism of action)?
- What brand names are available for sargramostim?
- Is sargramostim available as a generic drug?
- Do I need a prescription for sargramostim?
- What are the side effects of sargramostim?
- What is the dosage for sargramostim?
- Is sargramostim safe to take if I'm pregnant or breastfeeding?
- What else should I know about sargramostim?
What is sargramostim, and how does it work (mechanism of action)?
Sargramostim is a man-made form of the naturally-occurring protein, granulocyte, macrophage-colony stimulating factor (GM-CSF). GM-CSF is produced in the body by the immune system and stimulates the formation of white blood cells, including the granulocyte and the macrophage. Granulocytes and macrophages take part in the inflammatory reaction. They are responsible for detecting and destroying harmful bacteria and some fungi. Sargramostim belongs to a class of drugs called colony-stimulating factors because of their ability to stimulate cells in the bone marrow to multiply and form colonies. Sargramostim is man-made. It is a product of the genetic engineering of genes from fungi and is produced by recombinant DNA technology in bacteria. Other colony stimulating factors are epoetin alfa (Epogen, Procrit) that stimulate the formation of red blood cells and filgrastim (Neupogen) that also stimulates the formation of granulocytes and macrophages. The FDA approved sargramostim in March 1991.
What brand names are available for sargramostim?
Is sargramostim available as a generic drug?
GENERIC AVAILABLE: No
Do I need a prescription for sargramostim?
What are the side effects of sargramostim?
The most common side effects while taking sargramostim are:
- stomach pain,
- mild to moderate fever,
- muscle and bone pain.
- shortness of breath,
- weight loss,
- leg and arm swelling,
- injection site reactions,
- serious allergic reactions and
- abnormal heart beats.
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