samarium sm-153/lexidronam - injection, Quadramet
GENERIC NAME: SAMARIUM SM-153/LEXIDRONAM - INJECTION (sa-MARE-ee-um SM 153/lexi-DROH-nam)
BRAND NAME(S): Quadramet
USES: This product contains a radioactive medication. It is used to treat pain caused by cancer that has spread to the bone. It may help to make you more comfortable and may allow you to decrease the amount of pain medications you take.
HOW TO USE: This medication is injected into a vein as directed by your doctor. The dosage is based on your weight. Because this medication is radioactive, it is given only by specially trained health care professionals who must follow all proper use and handling instructions.Radioactive drug will be present in your urine for several hours after you receive the dose. Too much radiation can damage the bladder, so it is important to make sure the medication passes out of the bladder as soon as possible. Therefore, drink at least 2 glasses (16 ounces or 500 milliliters) of water or other fluid before receiving this medication, and urinate as often as possible after receiving the dose. Your doctor may decide to give these fluids by vein. Consult your doctor for details.Also, to make sure you and those around you are exposed to as little radiation as possible, take the following precautions for at least 12 hours after the dose. Use a toilet instead of a urinal, and flush the toilet several times after each use. Clean up any blood and spilled urine immediately. Wash your hands thoroughly after urinating or coming in contact with blood. If blood or urine gets onto clothing, wash the clothing separately from other clothes, or store them safely in a separate place for 1 to 2 weeks to give the radiation time to become less harmful. Consult your doctor or pharmacist for more information.You may have mild, temporary worsening of pain within the first 3 days after receiving the dose. You may start to feel pain relief 1 week after the dose. The best pain relief generally occurs after 3 to 4 weeks. Consult your doctor or pharmacist about the use of other pain medications for sudden attacks of pain.
Medically Reviewed by a Doctor on 4/16/2014
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Back to Medications Index