salsalate, Amigesic, Salflex, Argesic-SA, Marthritic, Salsitab, Artha-G

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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GENERIC NAME: salsalate

BRAND NAME: Amigesic, Salflex, Argesic-SA, Marthritic, Salsitab, Artha-G

DISCONTINUED BRANDS: Disalcid

DRUG CLASS AND MECHANISM: Salsalate is a nonsteroidal anti-inflammatory drug (NSAID) that is used for treating fever, pain, and inflammation in the body. Salsalate is converted in the body to salicylic acid which is its active form and is closely related to aspirin. Other NSAIDs include ibuprofen (Motrin), indomethacin (Indocin), nabumetone (Relafen), naproxen (Aleve) and several others. They work by reducing the levels of prostaglandins, chemicals produced by the body that are responsible for pain, fever, and inflammation. Salsalate blocks the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower concentrations of prostaglandins. As a consequence, inflammation, pain and fever are reduced. Salsalate is as strong as aspirin in reducing inflammation but has less effect on blood clotting than aspirin.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Tablets: 500 and 750 mg

STORAGE: Salsalate should be stored at room temperature, 15 C (59 F - 86 F).

PRESCRIBED FOR: Salsalate is used for treating rheumatoid arthritis and osteoarthritis. It also is used for the treatment of inflammation and pain resulting from soft tissue injuries, tendinitis, bursitis, and similar conditions.

Medically Reviewed by a Doctor on 10/30/2014

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