GENERIC NAME: salsalate
BRAND NAME: Amigesic, Salflex, Argesic-SA, Marthritic, Salsitab, Artha-G
DISCONTINUED BRANDS: Disalcid
DRUG CLASS AND MECHANISM: Salsalate is a nonsteroidal anti-inflammatory drug (NSAID) that is used for treating fever, pain, and inflammation in the body. Salsalate is converted in the body to salicylic acid which is its active form and is closely related to aspirin. Other NSAIDs include ibuprofen (Motrin), indomethacin (Indocin), nabumetone (Relafen), naproxen (Aleve) and several others. They work by reducing the levels of prostaglandins, chemicals produced by the body that are responsible for pain, fever, and inflammation. Salsalate blocks the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower concentrations of prostaglandins. As a consequence, inflammation, pain and fever are reduced. Salsalate is as strong as aspirin in reducing inflammation but has less effect on blood clotting than aspirin.
GENERIC AVAILABLE: Yes
PREPARATIONS: Tablets: 500 and 750 mg
STORAGE: Salsalate should be stored at room temperature, 15 C (59 F - 86 F).
PRESCRIBED FOR: Salsalate is used for treating rheumatoid arthritis and osteoarthritis. It also is used for the treatment of inflammation and pain resulting from soft tissue injuries, tendinitis, bursitis, and similar conditions.
Quick GuideRheumatoid Arthritis (RA) Pictures Slideshow
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Use the pill identifier tool on RxList.