Disclaimer

SALMETEROL/FLUTICASONE INHALATION-ORAL (cont.)

DRUG INTERACTIONS: Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: oral corticosteroids (e.g., dexamethasone, prednisone), beta-blockers (e.g., metoprolol, propranolol), MAO inhibitors (e.g., furazolidone, linezolid, moclobemide, phenelzine, procarbazine, selegiline, isocarboxazid, tranylcypromine), tricyclic antidepressants (e.g., amitriptyline, nortriptyline), "water pills" (diuretics such as furosemide, hydrochlorothiazide), HIV protease inhibitors (e.g., ritonavir, lopinavir), azole antifungals (e.g., itraconazole, ketoconazole), "adrenaline-like" stimulants (e.g., pseudoephedrine or ephedra). Use of this inhaler within two weeks after stopping MAO inhibitors or tricyclic antidepressants is not recommended, since these medications may increase the serious side effects of salmeterol. Check the labels on all your medicines (e.g., cough-and-cold products, diet aids) because they may contain ingredients that could increase your heart rate and blood pressure. Ask your pharmacist about the safe use of those products. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include: seizures, chest pain, fast/irregular heartbeat, severe muscle weakness, muscle cramping.

NOTES: Learn to use a peak flow meter, use it daily, and promptly report worsening asthma (such as readings in the yellow or red range, or increased use of quick-relief inhalers). Try to avoid irritants that may trigger an asthma attack such as smoke, pollen, pet dander, dust, or molds. Laboratory and/or medical tests (e.g., morning cortisol levels, IOP, children's rate of growth) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details. Do not share this medication with others.



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