- What is salmeterol, and how does it work (mechanism of action)?
- What brand names are available for salmeterol?
- Is salmeterol available as a generic drug?
- Do I need a prescription for salmeterol?
- What are the side effects of salmeterol?
- What is the dosage for salmeterol?
- Which drugs or supplements interact with salmeterol?
- Is salmeterol safe to take if I'm pregnant or breastfeeding?
- What else should I know about salmeterol?
What is salmeterol, and how does it work (mechanism of action)?
Asthma is a breathing problem involving narrowing of the airways. Airways are breathing passages that allow air to move in and out of the lungs. In patients with asthma, airways can be narrowed by accumulation of mucus, spasm of the muscles that surround these airways, or swelling of the lining of the airways. Airway narrowing lead to symptoms of shortness of breath, wheezing, cough, and congestion. Medications used in treating asthma open airways are called bronchodilators. Salmeterol is a bronchodilator of the beta-2 agonist type. Beta-2 agonists are medications that stimulate beta-2 receptors on the smooth muscle cells that line the airways, causing these muscle cells to relax, thus, opening airways.
Certain allergens (such as pollen) can cause airway narrowing by inducing release of histamine by mast cells. Histamine is a natural chemical that causes tissue swelling and other allergic reactions in the body when released into the tissue. Mast cells belong to a class of immune cells located around the airways. Salmeterol is an inhaled medication that blocks the release of histamine by the mast cells, thus preventing airway narrowing when exposed to allergens.
What brand names are available for salmeterol?
Is salmeterol available as a generic drug?
GENERIC AVAILABLE: no
Do I need a prescription for salmeterol?
What are the side effects of salmeterol?
Side effects include:
Throat and upper airway irritation can occur.
Use of long acting drugs like salmeterol may increase the risk of asthma-related death. Therefore, salmeterol should only be used in patients uncontrolled by other agents and who are using other long-term asthma-controlling medications such as an inhaled corticosteroid.
Quick GuideAsthma Symptoms, Causes, and Medications
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