How does Saffron work?
There isn't enough information to know how saffron might work.
Are there safety concerns?
Saffron seems safe for most people when used as a medicine. Some potential side effects include anxiety
, drowsiness, change in appetite, and headache
. Allergic reactions can occur in some people.
Ingesting large amounts of saffron can cause poisoning including yellow appearance of the skin, eyes, and mucous membranes; vomiting; dizziness
; bloody diarrhea
; bleeding from the nose, lips, and eyelids; numbness; and other serious side effects.
Do not take saffron if:
- You are pregnant or breast-feeding.
- You are allergic to related plants such as Lolium, Olea, or Salsola.
- You have bipolar disorder.
Dosing considerations for Saffron.
The following doses have been studied in scientific research:
- For depression: 30 mg/day of a specific saffron extract (Novin Zaferan Co, Iran). A different saffron extract 15 mg twice daily has also been used.
- For premenstrual syndrome (PMS): 15 mg of a specific ethanol saffron extract twice daily (Department of Cultivation and Development of Institute of Medicinal Plants, Tehran, Iran).
- For menstrual discomfort: 500 mg of a specific combination product containing saffron, celery seed and anise extracts (SCA, Gol Daro Herbal Medicine Laboratory) taken three times a day for the first three days of menstruation.
- For Alzheimer's disease: 30 mg/day of a specific saffron product (IMPIRAN, Iran).