Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.
Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.
What is the outcome (prognosis) of rotavirus infection?
Rotavirus infection is a
self-limited disease that resolves after three to nine days of symptoms. In rare
cases, severe dehydration accompanying rotavirus infection has led to death.
Recognition of the condition and proper supportive treatment (rehydration) can
prevent serious complications.
How can rotavirus infection be prevented?
Because the virus is so prevalent, it is very difficult or even impossible to prevent rotavirus infection. Even places with excellent standards of hygiene and sanitation can become contaminated. Vaccination is the most effective preventive measure.
An older vaccine to prevent rotavirus was withdrawn due to adverse effects. In August 1998, the U.S. Food and Drug Administration (FDA) approved a live virus vaccine for use in children at ages 2, 4, and 6 months. However, this recommendation was withdrawn in October 1999 because the vaccine appeared to increase the risk of intussusception (the prolapse or telescoping of a portion of the intestine into the immediately adjacent portion of the intestine). The vaccine known as RotaShield was withdrawn from the market in 1999.
However, in February 2006, the FDA approved a new rotavirus vaccine. This
vaccine RotaTeq™ is a live oral vaccine for use in children. The Advisory Committee on Immunization Practices (ACIP) voted to recommend a newly licensed vaccine to protect against rotavirus. Studies have shown that the vaccine prevents about 74% of all rotavirus cases, about 98% of severe rotavirus cases, and about 96% of hospitalizations due to rotavirus. Three doses of the rotavirus vaccine are recommended at 2, 4, and 6 months of age.
Abdominal pain is pain in the belly and can be acute or chronic. Causes include inflammation, distention of an organ, and loss of the blood supply to an organ. Abdominal pain can reflect a major problem with one of the organs in the abdomen such as the appendix, gallbladder, large and small intestine, pancreas, liver, colon, duodenum, and spleen.
Gastroenteritis (viral gastroenteritis, stomach flu) is an infection caused by a variety of viruses that results in vomiting and/or diarrhea. Even though it is often called the "stomach flu," it is not caused by the influenza viruses. Viruses that can cause gastroenteritis (stomach flu) include: rotaviruses, adenoviruses, caliciviruses, astroviruses, Norwalk virus, and a group of Noroviruses. Gastroenteritis is not caused by bacteria. The main symptoms of gastroenteritis include vomiting and watery diarrhea, however, headache, fever, and abdominal cramps (stomach ache) may also be present.
Diarrhea is a change is the frequency and looseness of bowel movements. Cramping, abdominal pain, and the sensation of rectal urgency are all symptoms of diarrhea. Absorbents and anti-motility medications are used to treat diarrhea.
Dehydration is the excessive loss of body water. There are a number of causes of dehydration including heat exposure, prolonged vigorous exercise, and some diseases of the gastrointestinal tract. The best way to treat dehydration is to prevent it from occurring.
Intussusception is the telescoping (prolapse) of a portion of the intestine within another immediately adjacent portion of intestine. Intussusception affects children between the ages of 3 months and 6 years of age. The causes of intussusception is not clearly understood. Symptoms of intussusception include bilious vomiting, "currant jelly stool," and colicky abdominal pain. Intussusception is an emergency requires immediate attention.
Reye's syndrome (RS, or Reye syndrome) is a sudden, sometimes fatal, disease of the brain with degeneration of the liver. Reye syndrome occurs in children and comes after the chickenpox or an influenza-type illness, is also associated with taking medications containing aspirin. Symptoms include vomiting, listlessness, irritability or combativeness, confusion, delirium, delusions, convulsions, and loss of consciousness. Treatment depends on early diagnosis and focuses on protecting the brain against irreversible damage by reducing brain swelling, reversing the metabolic injury, preventing complications in the lungs, and anticipating cardiac arrest.
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